TLR4 抗体
Quick Overview for TLR4 抗体 (ABIN119330)
抗原
See all TLR4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Affinity chromatography on Protein G
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内毒素水平
- < 0.01 EU/ug
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免疫原
- Ba/F3 cell line expressing TLR4 (CD284). Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
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亚型
- IgG2a
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应用备注
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Flow Cytometry: 1/10 - 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Immunoprecipitation. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, None, None
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- TLR4 (Toll-Like Receptor 4 (TLR4))
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别名
- CD284 / TLR4
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背景
- TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.Synonyms: Toll-like receptor 4
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NCBI登录号
- NM_138554
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UniProt
- O00206
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
抗原
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